This work is licensed under a Creative Commons Attribution 4.0 International License.
BF2d
General Information
DRACP ID DRACP00069
Peptide Name BF2d
Sequence TRSSRAGLQWPVGRVHRLLRKGGC
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Transducing peptide Cell-penetrating peptides
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 80-90% viablity=100 µM | MTT assay | 24 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C115H196N44O29S
Absent amino acids DEFIMNY
Common amino acids R
Mass 310158
Pl 12.68
Basic residues 7
Acidic residues 0
Hydrophobic residues 7
Net charge 7
Boman Index -6770
Hydrophobicity -64.17
Aliphatic Index 77.08
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 239.13
Polar residues 8
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 12417587
Title Translocation of analogues of the antimicrobial peptides magainin and buforin across human cell membranes
Year 2003
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.