This work is licensed under a Creative Commons Attribution 4.0 International License.
Agrocybin
General Information
DRACP ID DRACP00122
Peptide Name Agrocybin
Sequence ANDPQCLYGNVAAKF
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Agrocybe cylindracea
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | Not active up to 110 µM | Radioactive precursor assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C71H107N19O22S
Absent amino acids EHIMRSTW
Common amino acids A
Mass 186072
Pl 6.16
Basic residues 1
Acidic residues 1
Hydrophobic residues 6
Net charge 0
Boman Index -1364
Hydrophobicity -16.67
Aliphatic Index 65.33
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 106.43
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15629530
Title Agrocybin, an antifungal peptide from the edible mushroom Agrocybe cylindracea
Doi 10.1016/j.peptides.2004.09.011
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.