This work is licensed under a Creative Commons Attribution 4.0 International License.
EGFR-related peptide
General Information
DRACP ID DRACP00123
Peptide Name EGFR-related peptide
Sequence ERRP
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin EGFR-related peptide
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| PC-3 | Prostate carcinoma | Carcinoma | 30% Cell viability at 5 µg/ml | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism ERRP inhibits the growth of prostate cancer cells by attenuating EGFR signaling processes
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C22H40N10O7
Absent amino acids ACDFGHIKLMNQSTVWY
Common amino acids R
Mass 61030
Pl 10.4
Basic residues 2
Acidic residues 1
Hydrophobic residues 0
Net charge 1
Boman Index -3665
Hydrophobicity -352.5
Aliphatic Index 0
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15634655
Title Epidermal growth factor receptor-related peptide inhibits growth of PC-3 prostate cancer cells
Doi Not available
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.