This work is licensed under a Creative Commons Attribution 4.0 International License.
Antifungal lectin PVAP
General Information
DRACP ID DRACP00143
Peptide Name Antifungal lectin PVAP
Sequence SNDIYFNFQR
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Phaseolus vulgaris
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| L1210 | Mouse leukemia | Leukemia | IC50=3.6 µM | Radioactive precursor assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Mouse splenocytes: NA
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antifungal; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C59H82N16O18
Absent amino acids ACEGHKLMPTVW
Common amino acids FN
Mass 146410
Pl 6.34
Basic residues 1
Acidic residues 1
Hydrophobic residues 3
Net charge 0
Boman Index -3512
Hydrophobicity -105
Aliphatic Index 39
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 165.56
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16026901
Title An antifungal protein from flageolet beans
Doi 10.1016/j.peptides.2005.06.003
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.