This work is licensed under a Creative Commons Attribution 4.0 International License.
Cherimolacyclopeptide E
General Information
DRACP ID DRACP00144
Peptide Name Cherimolacyclopeptide E
Sequence PGLGFY
Sequence Length 6
UniProt ID P85003
PubChem CID Not available
Origin Annona cherimola (Custard apple) (Cherimoya)
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Human nasopharyngeal carcinoma | Nasopharyngeal carcinoma | Carcinoma | IC50=0.017 µM | Methylene Blue colourimetric assay | 72h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Pro1<--->Tyr6
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C33H44N6O8
Absent amino acids ACDEHIKMNQRSTVW
Common amino acids G
Mass 74211
Pl 6.09
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index 964
Hydrophobicity 48.33
Aliphatic Index 65
Half Life
Mammalian: 1.9 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 298
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16040066
Title Two cyclopeptides from the seeds of Annona cherimola
Doi 10.1016/j.phytochem.2005.06.011
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID DBAASPR_2979
This work is licensed under a Creative Commons Attribution 4.0 International License.