This work is licensed under a Creative Commons Attribution 4.0 International License.
lunatusin
General Information
DRACP ID DRACP00148
Peptide Name lunatusin
Sequence KTCENLADTFRGPCFATSNC
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Phaseolus lunatus
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50=5.71 µM | MTT assay | 4 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C90H140N26O31S3
Absent amino acids HIMQVWY
Common amino acids CT
Mass 251752
Pl 6.15
Basic residues 2
Acidic residues 2
Hydrophobic residues 5
Net charge 0
Boman Index -4111
Hydrophobicity -34
Aliphatic Index 29.5
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 125
Absorbance 280nm 6.58
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16269344
Title Lunatusin, a trypsin-stable antimicrobial peptide from lima beans (Phaseolus lunatus L.)
Doi 10.1016/j.peptides.2005.03.004
Year 2005
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.