This work is licensed under a Creative Commons Attribution 4.0 International License.
EGFR-lytic
General Information
DRACP ID DRACP00258
Peptide Name EGFR-lytic
Sequence YHWYGYTPQNVIGGGKLlLKlLKKLLKlLKKK
Sequence Length 32
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| MDA-MB-231 | Breast adenocarcinoma | Carcinoma | IC50=0.12 µM | ELISA assay | 60 min | 1 |
| MDA-MB-231 | Breast adenocarcinoma | Carcinoma | IC50=0.46 µM | ELISA assay | 15 min | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C165H262N42O33
Absent amino acids ACDEFMRS
Common amino acids K
Mass 391529
Pl 10.89
Basic residues 9
Acidic residues 0
Hydrophobic residues 9
Net charge 9
Boman Index -1966
Hydrophobicity -58.13
Aliphatic Index 94.38
Half Life
/
Extinction Coefficient cystines 9970
Absorbance 280nm 321.61
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21351323
Title Characterization of antilytic peptide antibody: application for the detection of lytic-based hybrid peptide in serum samples
Doi 10.1002/psc.1349
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.