This work is licensed under a Creative Commons Attribution 4.0 International License.
p85
General Information
DRACP ID DRACP00318
Peptide Name p85
Sequence LIAHNQVRQV
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Tumor cell line | Tumor | Carcinoma | Not available | ELISA assay | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Disrupting tumor-mediated mechanisms suppressing host immunity
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C51H88N18O14
Absent amino acids CDEFGKMPSTWY
Common amino acids QV
Mass 133810
Pl 10.55
Basic residues 2
Acidic residues 0
Hydrophobic residues 5
Net charge 2
Boman Index -1757
Hydrophobicity 3
Aliphatic Index 146
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21928125
Title Ontak reduces the immunosuppressive tumor environment and enhances successful therapeutic vaccination in HER-2/neu-tolerant mice
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.