This work is licensed under a Creative Commons Attribution 4.0 International License.
VitE-KkKK
General Information
DRACP ID DRACP00322
Peptide Name VitE-KkKK
Sequence KkKK
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| RAW 264.7 | Mouse leukemia | Leukemia | LC50=100 µM | XTT assay | 16h | 1 |
Hemolytic Activity Human erythrocytesl: 50% Hemolysis=60µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification VitE
C-terminal Modification Amidation
Other Modification k=D-Lys
Chiral Mix
Physicochemical Information
Formula C18H36N6O3
Absent amino acids ACDEFGHILMNPQRSTVWY
Common amino acids K
Mass 43821
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 0
Net charge 3
Boman Index -1665
Hydrophobicity -292.5
Aliphatic Index 0
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22006001
Title Ultrashort peptide bioconjugates are exclusively antifungal agents and synergize with cyclodextrin and amphotericin B
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.