This work is licensed under a Creative Commons Attribution 4.0 International License.
Alliumin
General Information
DRACP ID DRACP00449
Peptide Name Alliumin
Sequence DDFLCAGGCL
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Allium sativum
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | NA at 40 µM | Radioactive precursor assay | 48h | 1 |
| L1210 | Mouse leukemia | Leukemia | IC50=8.33 µM | Radioactive precursor assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C42H64N10O15S2
Absent amino acids EHIKMNPQRSTVWY
Common amino acids CDGL
Mass 117389
Pl 3.49
Basic residues 0
Acidic residues 2
Hydrophobic residues 4
Net charge -2
Boman Index 163
Hydrophobicity 94
Aliphatic Index 88
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 125
Absorbance 280nm 13.89
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23269800
Title Enhancement of antiviral activity of human alpha-defensin 5 against herpes simplex virus 2 by arginine mutagenesis at adaptive evolution sites
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.