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BP325
General Information
DRACP ID DRACP00473
Peptide Name BP325
Sequence CLBKKLFKKILKKL
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Coupling peptide
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| E42/02 | Horse sarcoid | Sarcoma | IC50>>100 µM | MTT assay | 30 min | 1 |
| E42/02 | Horse sarcoid | Sarcoma | IC50>>100 µM | MTT assay | 2 h | 1 |
| E42/02 | Horse sarcoid | Sarcoma | IC50>>100 µM | MTT assay | 4 h | 1 |
| E42/02 | Horse sarcoid | Sarcoma | IC50>>100 µM | MTT assay | 24 h | 1 |
| CAPAN-1 | Pancreatic ductal adenocarcinoma | Carcinoma | IC50=13.7 ± 2.4 µM | MTT assay | 48 h | 1 |
| MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50=12.0 ± 2.7 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity NIH 3T3: IC50=20.6 ± 3.3 µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C78H141N19O13S
Absent amino acids ADEGHMNPQRSTVWY
Common amino acids K
Mass 181723
Pl 11.1
Basic residues 6
Acidic residues 0
Hydrophobic residues 6
Net charge 6
Boman Index -444
Hydrophobicity 11.43
Aliphatic Index 139.29
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24480922
Title Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.