This work is licensed under a Creative Commons Attribution 4.0 International License.
LTX-328
General Information
DRACP ID DRACP00496
Peptide Name LTX-328
Sequence KAQXQKQAW
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Immune system stimulating peptides
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| FEMX-I | Melanoma | Carcinoma | IC50>350 µM | MTT assay | 6 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification X=Dip=diphenylalanine
Chiral L
Physicochemical Information
Formula C44H68N14O11
Absent amino acids CDEFGHILMNPRSTVY
Common amino acids Q
Mass 122200
Pl 10.81
Basic residues 2
Acidic residues 0
Hydrophobic residues 3
Net charge 2
Boman Index -2177
Hydrophobicity -173.33
Aliphatic Index 22.22
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 687.5
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24676901
Title Complete regression and systemic protective immune responses obtained in B16 melanomas after treatment with LTX-315
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.