This work is licensed under a Creative Commons Attribution 4.0 International License.
T Peptide
General Information
DRACP ID DRACP00498
Peptide Name T Peptide
Sequence TKPRKTKPRKTKPRKTKPR
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Tuftsin derivative
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Hep-G2 | Hepatoblastoma; Hepatoblastoma | Blastoma | 69.6% maximum inhibitory rate at 8 mg/kg | MTT assay | 48 h | 1 |
| HT-29 | Colon adenocarcinoma | Carcinoma | 70% maximum inhibitory rate at 8 mg/kg | MTT assay | 48 h | 1 |
| BGC-823 | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 67.2% maximum inhibitory rate at 8 mg/kg | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C102H190N38O24
Absent amino acids ACDEFGHILMNQSVWY
Common amino acids K
Mass 265407
Pl 13
Basic residues 11
Acidic residues 0
Hydrophobic residues 0
Net charge 11
Boman Index -10881
Hydrophobicity -286.84
Aliphatic Index 0
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24714081
Title Anticancer activity of tuftsin-derived T peptide in postoperative residual tumors
Doi 10.1097/CAD.0000000000000111
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.