WKX

General Information


DRACP ID  DRACP00530

Peptide Name   WKX

Sequence  WKX

Sequence Length  3

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
MM1.S Plasma cell myeloma; Multiple myeloma Carcinoma 25% Inhibition=10µM Not available Not available 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Picolinoyl

C-terminal Modification  Free

Other Modification  X=MET-Boro

Chiral  L



Physicochemical Information


Formula  C17H22N4O2

Absent amino acids  ACDEFGHILMNPQRSTVY

Common amino acids  KWX

Mass  46024

Pl  9.7

Basic residues  1

Acidic residues  0

Hydrophobic residues  1

Net charge  1

Boman Index  -322

Hydrophobicity  -160

Aliphatic Index  0

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  2750

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25759383

Title  Cleavage Specificity of Mycobacterium tuberculosis ClpP1P2 Protease and Identification of Novel Peptide Substrates and Boronate Inhibitors with Anti-bacterial Activity

Doi 10.1074/jbc.M114.625640

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.