This work is licensed under a Creative Commons Attribution 4.0 International License.
Peptide 35409
General Information
DRACP ID DRACP00661
Peptide Name Peptide 35409
Sequence RYRRKKKMKKALQYIKLLKE
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | Not active up to 44 µg/ml | Resazurine assay | 72h | 1 |
| HepG2 | Hepatoblastoma | Blastoma | Not active up to 44 µg/ml | Resazurine assay | 72h | 1 |
Hemolytic Activity Human erythrocytes: 14% Hemolysis=350µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C120H213N37O26S
Absent amino acids CDFGHNPSTVW
Common amino acids K
Mass 296138
Pl 11.49
Basic residues 10
Acidic residues 1
Hydrophobic residues 5
Net charge 9
Boman Index -7240
Hydrophobicity -154
Aliphatic Index 83
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 2980
Absorbance 280nm 156.84
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28066341
Title A New Synthetic Peptide Having Two Target of Antibacterial Action in E. coli ML35
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.