Brevinin1 HYba2

General Information


DRACP ID  DRACP00662

Peptide Name   Brevinin1 HYba2

Sequence  FFPGIIKVAGAILPTAICAITKRC

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
Hep 3B Childhood hepatocellular carcinoma Carcinoma 85% Cytotoxicity=100µg/ml MTT assay Not available 1

Hemolytic Activity  Human erythrocytes: 60% Hemolysis=50µM; 85% Hemolysis=100µM

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  DRACP00662

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C117H195N29O27S2

Absent amino acids  DEHMNQSWY

Common amino acids  I

Mass  291459

Pl  9.76

Basic residues  3

Acidic residues  0

Hydrophobic residues  13

Net charge  3

Boman Index  2004

Hydrophobicity  127.5

Aliphatic Index  126.25

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  125

Absorbance 280nm  5.43

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28072492

Title  Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae)

Doi 10.1111/cbdd.12937

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.