This work is licensed under a Creative Commons Attribution 4.0 International License.
Brevinin1 HYba1 AMD
General Information
DRACP ID DRACP00665
Peptide Name Brevinin1 HYba1 AMD
Sequence FFPGIIKVASAILPTAICAITKRC
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Hydrophylax bahuvistara
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| Hep 3B | Childhood hepatocellular carcinoma | Carcinoma | 85% Cytotoxicity=100µg/ml | MTT assay | Not available | 1 |
Hemolytic Activity Human erythrocytes:30% Hemolysis=50µM; 40% Hemolysis=100µM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C118H197N29O28S2
Absent amino acids DEHMNQWY
Common amino acids I
Mass 294461
Pl 9.76
Basic residues 3
Acidic residues 0
Hydrophobic residues 13
Net charge 3
Boman Index 1570
Hydrophobicity 125.83
Aliphatic Index 126.25
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 125
Absorbance 280nm 5.43
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28072492
Title Identification and characterization of novel host defense peptides from the skin secretion of the fungoid frog, Hydrophylax bahuvistara (Anura: Ranidae)
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.