This work is licensed under a Creative Commons Attribution 4.0 International License.
AM-CATH21
General Information
DRACP ID DRACP00666
Peptide Name AM-CATH21
Sequence GLFKKLRRKIKKGFKKIFKRL
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | Not active up to 100 µg/ml | MTT assay | 24h | 1 |
Hemolytic Activity Sheep erythrocytes(Not active up to 300 µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C127H222N38O22
Absent amino acids ACDEHMNPQSTVWY
Common amino acids K
Mass 299031
Pl 12.85
Basic residues 11
Acidic residues 0
Hydrophobic residues 8
Net charge 11
Boman Index -5374
Hydrophobicity -79.52
Aliphatic Index 92.86
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28089718
Title Cathelicidin antimicrobial peptide from Alligator mississippiensis has antibacterial activity against multi-drug resistant Acinetobacter baumanii and Klebsiella pneumoniae
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.