This work is licensed under a Creative Commons Attribution 4.0 International License.
[D-Trp]CJ-15,208
General Information
DRACP ID DRACP00750
Peptide Name [D-Trp]CJ-15,208
Sequence FpFw
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| PC-3 | Prostate carcinoma | Carcinoma | IC50=16.5±0.7 µM | WST-1 assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Not available
N-terminal Modification Lactam
C-terminal Modification Lactam
Other Modification p=D-Proline; w=D-Tryptophane
Chiral Mix
Physicochemical Information
Formula C18H16N2O
Absent amino acids ACDEGHIKLMNPQRSTVWY
Common amino acids F
Mass 33002
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 2
Net charge 0
Boman Index 596
Hydrophobicity 140
Aliphatic Index 0
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28692379
Title Macrocyclic peptides decrease c-Myc protein levels and reduce prostate cancer cell growth
Doi 10.1080/15384047.2017.1345384
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.