This work is licensed under a Creative Commons Attribution 4.0 International License.
Bacteriocin ASP-1
General Information
DRACP ID DRACP00784
Peptide Name Bacteriocin ASP-1
Sequence FTVAXFI
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Bacillus subtilis URID 12.1
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | IC50=192µg/ml | MTS assay | 24h | 1 |
| MCF-7 | Invasive breast carcinoma of no special type | Carcinoma | IC50=280µg/ml | MTS assay | 24h | 1 |
Hemolytic Activity Human erythrocytes: <5% Hemolysis=128µg/ml; 30% Hemolysis=256µg/ml
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond LCB: X(5)<--->Ile7
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification X=dehydrobutyrine
Chiral L
Physicochemical Information
Formula C36H50N6O7
Absent amino acids CDEGHKLMNPQRSWY
Common amino acids F
Mass 89603
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 5
Net charge 0
Boman Index 1416
Hydrophobicity 220
Aliphatic Index 111.43
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28887200
Title Purification and characterization of a novel anti-staphylococcal peptide (ASP-1) from bacillus sp. URID 12.1
Doi 10.1016/j.ijantimicag.2017.08.030
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.