This work is licensed under a Creative Commons Attribution 4.0 International License.
12-(Lys)4-12
General Information
DRACP ID DRACP00983
Peptide Name 12-(Lys)4-12
Sequence KKKK
Sequence Length 4
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HeLa | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | 0% Killing=32µM; 15% Killing=64µM; 95% Killing=128µM | Not available | Not available | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification C12
C-terminal Modification C12
Other Modification None
Chiral L
Physicochemical Information
Formula C24H50N8O5
Absent amino acids ACDEFGHILMNPQRSTVWY
Common amino acids K
Mass 58440
Pl 11.28
Basic residues 4
Acidic residues 0
Hydrophobic residues 0
Net charge 4
Boman Index -2220
Hydrophobicity -390
Aliphatic Index 0
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32193931
Title Gemini Peptide Amphiphiles with Broad-Spectrum Antimicrobial Activity and Potent Antibiofilm Capacity
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.