This work is licensed under a Creative Commons Attribution 4.0 International License.
anti-HIV AMPs Molecule 3
General Information
DRACP ID DRACP00985
Peptide Name anti-HIV AMPs Molecule 3
Sequence RWKLFKKIEKVGRNVRDGLIKAGPAIAVIGQAKSLGK
Sequence Length 37
UniProt ID Not available
PubChem CID Not available
Origin Bombyx mori
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | 20% Killing=100 µg/ml | MTT assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity HEK293T: 40% Killing=100µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C185H318N56O45
Absent amino acids CHMTY
Common amino acids K
Mass 468924
Pl 11.86
Basic residues 10
Acidic residues 2
Hydrophobic residues 16
Net charge 8
Boman Index -5091
Hydrophobicity -21.89
Aliphatic Index 108.11
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 152.78
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32322274
Title Antibacterial Activity of Rationally Designed Antimicrobial Peptides
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.