EtCec1-NH2

General Information


DRACP ID  DRACP00987

Peptide Name   EtCec1-NH2

Sequence  GFLKKIGKKLEGAVQRTRDATIQTIAVAQAAANVAATAKQ

Sequence Length  40

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
HepG2 Hepatoblastoma Blastoma Not active up to 1655 µg/ml CellTiter-Glo ATP assay 24h 1

Hemolytic Activity  Human erythrocytes: Not active up to 1024 µg/ml

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP00987

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C181H314N56O54

Absent amino acids  CHMPSWY

Common amino acids  A

Mass  483470

Pl  11.34

Basic residues  7

Acidic residues  2

Hydrophobic residues  19

Net charge  5

Boman Index  -5158

Hydrophobicity  -6.25

Aliphatic Index  95.5

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32344933

Title  Antimicrobial Peptides from Rat-Tailed Maggots of the Drone Fly Eristalis tenax Show Potent Activity against Multidrug-Resistant Gram-Negative Bacteria

Doi 10.3390/microorganisms8050626

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.