This work is licensed under a Creative Commons Attribution 4.0 International License.
Esculentin (1-21)[L14l,S17s]
General Information
DRACP ID DRACP01006
Peptide Name Esculentin (1-21)[L14l,S17s]
Sequence GIFSKLAGKKIKNlLIsGLKG
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | 10% Cell death=150 µM | MTT assay | 24h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification l=D-Leu; s=D-Ser
Chiral Mix
Physicochemical Information
Formula C93H161N25O20
Absent amino acids CDEHMPQRTVWY
Common amino acids K
Mass 230639
Pl 11.4
Basic residues 5
Acidic residues 0
Hydrophobic residues 8
Net charge 5
Boman Index 28
Hydrophobicity 19.52
Aliphatic Index 116.19
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32722535
Title Frog Skin-Derived Peptides Against Corynebacterium jeikeium: Correlation between Antibacterial and Cytotoxic Activities
Doi 10.3390/antibiotics9080448
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.