This work is licensed under a Creative Commons Attribution 4.0 International License.
Granuliberin-SSa
General Information
DRACP ID DRACP01008
Peptide Name Granuliberin-SSa
Sequence FIFLPIFRRPVS
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Glandirana susurra
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HepG2 | Hepatoblastoma | Blastoma | 50.5% Killing=32µg/ml | MTT assay | 24h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity COS-7: 88.5% Killing=32µg/ml; CPAE: 99.2% Killing=32µg/ml
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C75H114N18O14
Absent amino acids ACDEGHKMNQTWY
Common amino acids F
Mass 168821
Pl 12.5
Basic residues 2
Acidic residues 0
Hydrophobic residues 7
Net charge 2
Boman Index -550
Hydrophobicity 103.33
Aliphatic Index 121.67
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 32751229
Title Antimicrobial Property and Mode of Action of the Skin Peptides of the Sado Wrinkled Frog, Glandirana susurra, against Animal and Plant Pathogens
Doi 10.3390/antibiotics9080457
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.