Cathelicidin-like peptide Bal1

General Information


DRACP ID  DRACP01032

Peptide Name   Cathelicidin-like peptide Bal1

Sequence  RRIRFRPPRLPRPRPRPWIPPRFPFPRIPGKR

Sequence Length  32

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
MEC-1 Chronic lymphocytic leukemia; B-cell chronic lymphocytic leukemia Leukemia 95% killing=32μM MTT assay 20h 1

Hemolytic Activity  Human erythrocytes:0% Hemolysis=32µM

Normal (non-cancerous) Cytotoxicity  HaCat: 0% Killing=32µM

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01032

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C191H307N67O33

Absent amino acids  ACDEHMNQSTVY

Common amino acids  PR

Mass  462301

Pl  13.5

Basic residues  12

Acidic residues  0

Hydrophobic residues  8

Net charge  12

Boman Index  -13778

Hydrophobicity  -145.63

Aliphatic Index  48.75

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  177.42

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 33036159

Title  Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens

Doi 10.3390/ijms21197367

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.