This work is licensed under a Creative Commons Attribution 4.0 International License.
Pom-1
General Information
DRACP ID DRACP01034
Peptide Name Pom-1
Sequence KCAGSIAWAIGSGLFGGAKLIKIKKYIAELGGLQ
Sequence Length 34
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| TZM-bl | Human papillomavirus-related endocervical adenocarcinoma | Carcinoma | IC50=40.16µg/ml | MTT assay | 48h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Vero E6: 50% Cytotoxicity=438 µM
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C161H265N41O41S
Absent amino acids DHMNPRTV
Common amino acids G
Mass 405203
Pl 10.38
Basic residues 5
Acidic residues 1
Hydrophobic residues 16
Net charge 4
Boman Index 1946
Hydrophobicity 55.59
Aliphatic Index 117.94
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 6990
Absorbance 280nm 211.82
Polar residues 11
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33113998
Title New Antibacterial Peptides from the Freshwater Mollusk Pomacea poeyana (Pilsbry, 1927)
Year 2020
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.