This work is licensed under a Creative Commons Attribution 4.0 International License.
HS6
General Information
DRACP ID DRACP01045
Peptide Name HS6
Sequence GAISLAKLQINeG
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP Cancer targeted peptides
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| CT26 | Mouse colon adenocarcinoma | Carcinoma | IC50=0.71±0.22 µM | MTT assay | 24, 48, 72h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target programmed cell death protein 1
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Not available
N-terminal Modification Acetylization
C-terminal Modification Amidation
Other Modification C,N-terminal lactam peptide; e=D-Glutamic acid
Chiral Mix
Physicochemical Information
Formula C52H91N15O15
Absent amino acids CDEFHMPRTVWY
Common amino acids AGIL
Mass 138063
Pl 9.7
Basic residues 1
Acidic residues 0
Hydrophobic residues 6
Net charge 1
Boman Index 405
Hydrophobicity 59.23
Aliphatic Index 135.38
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 33360579
Title Design, synthesis and evaluation of PD-L1 peptide antagonists as new anticancer agents for immunotherapy
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.