This work is licensed under a Creative Commons Attribution 4.0 International License.
C-ori
General Information
DRACP ID DRACP01066
Peptide Name C-ori
Sequence VTFVLIAAK
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Cordyceps militaris
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HT-29 | Colon adenocarcinoma | Carcinoma | IC50=114.9±1.5 µM | MTT assay | 24, 48, 72h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C47H80N10O11
Absent amino acids CDEGHMNPQRSWY
Common amino acids AV
Mass 110410
Pl 9.7
Basic residues 1
Acidic residues 0
Hydrophobic residues 7
Net charge 1
Boman Index 1640
Hydrophobicity 205.56
Aliphatic Index 173.33
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34641308
Title Virtual Screening for Biomimetic Anti-Cancer Peptides from Cordyceps militaris Putative Pepsinized Peptidome and Validation on Colon Cancer Cell Line
Year 2021
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.