This work is licensed under a Creative Commons Attribution 4.0 International License.
MSI-238
General Information
DRACP ID DRACP01082
Peptide Name MSI-238
Sequence gigkflkkakkfakafvkiinn
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin African clawed frog Xenopus laevis skin
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| A549 | Lung adenocarcinoma | Carcinoma | IC50=6 µM | MTT assay | 48 h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism A mechanism which appears to be related to short duration non-receptor-driven contact with target cell membranes.
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral D
Physicochemical Information
Formula H-42O-21
Absent amino acids ACDEFGHIKLMNPQRSTVWY
Common amino acids ACDEFGHIKLMNPQRSTVWYX
Mass -360
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 0
Net charge 0
Boman Index 0
Hydrophobicity 0
Aliphatic Index 0
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 8319212
Title Anticancer efficacy of Magainin2 and analogue peptides
Doi Not available
Year 1993
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.