Peptide Libraray

BCP-A

General Information

DRACP ID DRACP01099

Peptide Name BCP-A

Sequence WPP

Sequence Length 3

UniProt ID Not available

PubChem CID Not available

Origin hydrolysate of blood clam (Tegillarca granosa) muscle

Type Native peptide

Classification

Active ACP

Activity Information

Cell Line	Disease	Cancer Classified	Activity	Assay	Testing Time	Literature
PC-3	Prostate carcinoma	Carcinoma	IC50=1.99 mg/mL	MTT assay	24h	1
DU145	Prostate carcinoma	Carcinoma	IC50=2.80 mg/mL	MTT assay	24h	1
NCI-H1299	Lung large cell carcinoma	Carcinoma	IC50=3.3 mg/mL	MTT assay	24h	1
HeLa	Human papillomavirus-related endocervical adenocarcinoma	Carcinoma	IC50=2.54 mg/mL	MTT assay	24h	1

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity NIH 3T3: Has hardly any cytotoxicity on normal cells.

Target Not available

Affinity Not available

Mechanism Not available

Nature Anticancer

Structure Information

PDB ID Not available

Predicted Structure DRACP01099

Helicity Not available

Linear/Cyclic Linear

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C21H26N4O4

Absent amino acids ACDEFGHIKLMNQRSTVY

Common amino acids P

Mass 43431

Pl 6.11

Basic residues 0

Acidic residues 0

Hydrophobic residues 1

Net charge 0

Boman Index 233

Hydrophobicity -136.67

Aliphatic Index 0

Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min

Extinction Coefficient cystines 5500

Absorbance 280nm 2750

Polar residues 0

Amino acid distribution

Literature Information

Literature 1

Pubmed ID Not available

Title Antioxidant and anticancer peptides from the protein hydrolysate of blood clam (Tegillarca granosa) muscle

Doi 10.1016/j.jff.2015.03.045

Year 2015

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available