This work is licensed under a Creative Commons Attribution 4.0 International License.
P19
General Information
DRACP ID DRACP01100
Peptide Name P19
Sequence SLPQNIPPLTQTPVVVPPF
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synbiotic yoghurt
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HT-29 | Colon adenocarcinoma | Carcinoma | Antiproliferative acitivity (%)=38.55±1.75%, Peptide concentration 3 mg/mL | MTS assay | 72h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C97H154N22O26
Absent amino acids ACDEGHKMRWY
Common amino acids P
Mass 236565
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 7
Net charge 0
Boman Index 360
Hydrophobicity 27.37
Aliphatic Index 107.37
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Antioxidant peptides isolated from synbiotic yoghurt exhibit antiproliferative activities against HT-29 colon cancer cells
Doi 10.1016/j.idairyj.2016.08.003
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.