This work is licensed under a Creative Commons Attribution 4.0 International License.
P17
General Information
DRACP ID DRACP01101
Peptide Name P17
Sequence YQEPVLGPVRGPFPIIV
Sequence Length 17
PubChem CID Not available
Origin Synbiotic yoghurt
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| HT-29 | Colon adenocarcinoma | Carcinoma | Antiproliferative acitivity (%)=41.49±2.18%, Peptide concentration 3 mg/mL | MTS assay | 72h | 1 |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C91H141N21O22
Absent amino acids ACDHKMNSTW
Common amino acids P
Mass 216681
Pl 6.4
Basic residues 1
Acidic residues 1
Hydrophobic residues 7
Net charge 0
Boman Index 433
Hydrophobicity 48.24
Aliphatic Index 120
Half Life
Mammalian: 1.9 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 93.13
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Antioxidant peptides isolated from synbiotic yoghurt exhibit antiproliferative activities against HT-29 colon cancer cells
Doi 10.1016/j.idairyj.2016.08.003
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.