YALPAG

General Information


DRACP ID  DRACP01117

Peptide Name   YALPAG

Sequence  YALPAG

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Type  Native peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
PC-3 Prostate carcinoma Carcinoma IC50=71.2 μM (42.0 mg/mL) MTT assay 48h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01117

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C28H42N6O8

Absent amino acids  CDEFHIKMNQRSTVW

Common amino acids  A

Mass  68005

Pl  6.09

Basic residues  0

Acidic residues  0

Hydrophobic residues  3

Net charge  0

Boman Index  934

Hydrophobicity  68.33

Aliphatic Index  98.33

Half Life 
  Mammalian: 20 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  298

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Doi 10.1016/j.jff.2014.06.010

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.