YALPAH

General Information


DRACP ID  DRACP01118

Peptide Name   YALPAH

Sequence  YALPAH

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Type  Native peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
PC-3 Prostate carcinoma Carcinoma IC50=16.9 μM (11.3 mg/mL) MTT assay 48h 1

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01118

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C32H46N8O8

Absent amino acids  CDEFGIKMNQRSTVW

Common amino acids  A

Mass  76014

Pl  7.54

Basic residues  1

Acidic residues  0

Hydrophobic residues  3

Net charge  1

Boman Index  374

Hydrophobicity  21.67

Aliphatic Index  98.33

Half Life 
  Mammalian: 2.8 hour
  Yeast: 10 min
  E.coli: 2 min

Extinction Coefficient cystines  1490

Absorbance 280nm  298

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Isolation and identification of an antiproliferative peptide derived from heated products of peptic hydrolysates of half-fin anchovy (Setipinna taty)

Doi 10.1016/j.jff.2014.06.010

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.