YALPAH

General Information


DRACP ID  DRACP01124

Peptide Name   YALPAH

Sequence  YALPAH

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Yellow crucian carp protein

Type  Native peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
PC-3 Prostate carcinoma Carcinoma IC50=6.32 μM/mL MTT assay Not available Patent

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Inhibit cell proliferation and inducing apoptosis

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01124

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C32H46N8O8

Absent amino acids  CDEFGIKMNQRSTVW

Common amino acids  A

Mass  76014

Pl  7.54

Basic residues  1

Acidic residues  0

Hydrophobic residues  3

Net charge  1

Boman Index  374

Hydrophobicity  21.67

Aliphatic Index  98.33

Half Life 
  Mammalian: 100 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  298

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN103665103B

Patent Title  Method for separating out prostatic cancer (PC)-3 anticancer peptide by utilizing thermal reactant of setipinna taty antibacterial peptide liquid and anticancer peptide obtained by using method

Other Iinformation  Granted Patent; Family: 2s / 2ex; Family Jurisdictions: CN; Legal Status: Active; Application No: 201310460838; Filed: Sep 29, 2013; Published: Apr 6, 2016; Earliest Priority: Sep 29, 2013; Granted: Apr 6, 2016

Other Published ID  CN103665103B 




DRACP is developed by Dr.Zheng's team.