YALPAH
General Information
DRACP ID DRACP01124
Peptide Name YALPAH
Sequence YALPAH
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Yellow crucian carp protein
Type Native peptide
Classification
Active ACP
Activity Information
Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
---|---|---|---|---|---|---|
PC-3 | Prostate carcinoma | Carcinoma | IC50=6.32 μM/mL | MTT assay | Not available | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Inhibit cell proliferation and inducing apoptosis
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C32H46N8O8
Absent amino acids CDEFGIKMNQRSTVW
Common amino acids A
Mass 76014
Pl 7.54
Basic residues 1
Acidic residues 0
Hydrophobic residues 3
Net charge 1
Boman Index 374
Hydrophobicity 21.67
Aliphatic Index 98.33
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 298
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN103665103B
Patent Title Method for separating out prostatic cancer (PC)-3 anticancer peptide by utilizing thermal reactant of setipinna taty antibacterial peptide liquid and anticancer peptide obtained by using method
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: CN; Legal Status: Active; Application No: 201310460838; Filed: Sep 29, 2013; Published: Apr 6, 2016; Earliest Priority: Sep 29, 2013; Granted: Apr 6, 2016
Other Published ID CN103665103B