This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO 19 from EP1783140A3
General Information
DRACP ID DRACP01141
Peptide Name SEQ ID NO 19 from EP1783140A3
Sequence ADGAPRPGAPLA
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Screen of phage display peptide library
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| tumor cell | Tumor | Sarcoma | Tumor growth inhibitory activity as show in fig.6; fig.7; fig.8 | Tumor growth inhibition assay | 14 days | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C47H77N15O15
Absent amino acids CEFHIKMNQSTVWY
Common amino acids A
Mass 128862
Pl 6.34
Basic residues 1
Acidic residues 1
Hydrophobic residues 5
Net charge 0
Boman Index -960
Hydrophobicity -21.67
Aliphatic Index 65.83
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP1783140A3
Patent Title Neovascular-specific peptides
Other Iinformation Search Report; Family: 16s / 16ex; Family Jurisdictions: EP, CA, ES, JP, CY, DK, US, DE, WO, AT, PT; Legal Status: Discontinued; Application No: 06021030; Filed: Oct 15, 1999; Published: Jul 11, 2007; Earliest Priority: Oct 16, 1998
Other Published ID EP1783140A3 AT453667T CA2347136A1 CA2622786A1 CY1109881T1 DK1122262T3 EP1122262A1 EP1122262A4 EP1122262B1 ES2337321T3 JP4439120B2 PT1122262E US6753310B1 WO0023476A1
This work is licensed under a Creative Commons Attribution 4.0 International License.