SEQ ID NO 19 from EP1783140A3

General Information


DRACP ID  DRACP01141

Peptide Name   SEQ ID NO 19 from EP1783140A3

Sequence  ADGAPRPGAPLA

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Screen of phage display peptide library

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Cell Line Disease Cancer Classified Activity Assay Testing Time Literature
tumor cell Tumor Sarcoma Tumor growth inhibitory activity as show in fig.6; fig.7; fig.8 Tumor growth inhibition assay 14 days Patent

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01141

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C47H77N15O15

Absent amino acids  CEFHIKMNQSTVWY

Common amino acids  A

Mass  128862

Pl  6.34

Basic residues  1

Acidic residues  1

Hydrophobic residues  5

Net charge  0

Boman Index  -960

Hydrophobicity  -21.67

Aliphatic Index  65.83

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID EP1783140A3

Patent Title  Neovascular-specific peptides

Other Iinformation  Search Report; Family: 16s / 16ex; Family Jurisdictions: EP, CA, ES, JP, CY, DK, US, DE, WO, AT, PT; Legal Status: Discontinued; Application No: 06021030; Filed: Oct 15, 1999; Published: Jul 11, 2007; Earliest Priority: Oct 16, 1998

Other Published ID  EP1783140A3  AT453667T  CA2347136A1  CA2622786A1  CY1109881T1  DK1122262T3  EP1122262A1  EP1122262A4  EP1122262B1  ES2337321T3  JP4439120B2  PT1122262E  US6753310B1  WO0023476A1 




DRACP is developed by Dr.Zheng's team.