This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO 5 from EP1783140A3
General Information
DRACP ID DRACP01145
Peptide Name SEQ ID NO 5 from EP1783140A3
Sequence DRWRPALPVVLFPLH
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Screen of phage display peptide library
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| tumor cell | Tumor | Sarcoma | Tumor growth inhibitory activity as show in fig.6; fig.7; fig.8 | Tumor growth inhibition assay | 14 days | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C88H134N24O18
Absent amino acids CEGIKMNQSTY
Common amino acids LP
Mass 206608
Pl 10.4
Basic residues 3
Acidic residues 1
Hydrophobic residues 8
Net charge 2
Boman Index -1326
Hydrophobicity 20
Aliphatic Index 123.33
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 392.86
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP1783140A3
Patent Title Neovascular-specific peptides
Other Iinformation Search Report; Family: 16s / 16ex; Family Jurisdictions: EP, CA, ES, JP, CY, DK, US, DE, WO, AT, PT; Legal Status: Discontinued; Application No: 06021030; Filed: Oct 15, 1999; Published: Jul 11, 2007; Earliest Priority: Oct 16, 1998
Other Published ID EP1783140A3 AT453667T CA2347136A1 CA2622786A1 CY1109881T1 DK1122262T3 EP1122262A1 EP1122262A4 EP1122262B1 ES2337321T3 JP4439120B2 PT1122262E US6753310B1 WO0023476A1
This work is licensed under a Creative Commons Attribution 4.0 International License.