This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO: 3 from EP2716297B1
General Information
DRACP ID DRACP01159
Peptide Name SEQ ID NO: 3 from EP2716297B1
Sequence LNQEEARKSE
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Screen of phage display peptide library
Type Native peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| PC-3 | Prostate carcinoma | Carcinoma | As show in fig6 | Mouse model anti-tumor assay | 42 days | Patent |
| LNCaP | Prostate carcinoma | Carcinoma | As show in fig6 | Mouse model anti-tumor assay | 42 days | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C48H82N16O20
Absent amino acids CDFGHIMPTVWY
Common amino acids E
Mass 136398
Pl 4.48
Basic residues 2
Acidic residues 3
Hydrophobic residues 2
Net charge -1
Boman Index -4975
Hydrophobicity -211
Aliphatic Index 49
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP2524926B1
Patent Title Anticancer Peptide Sequence
Other Iinformation Granted Patent; Family: 7s / 7ex; Family Jurisdictions: EP, KR, WO; Legal Status: Active; Application No: 10843287; Filed: Dec 27, 2010; Published: Mar 9, 2016; Earliest Priority: Jan 12, 2010; Granted: Mar 9, 2016
Other Published ID EP2524926A4 EP2524926B1 KR101815322B1 KR20110082954A WO2011087222A2 WO2011087222A3
This work is licensed under a Creative Commons Attribution 4.0 International License.