This work is licensed under a Creative Commons Attribution 4.0 International License.
D-Glu-Fniii14
General Information
DRACP ID DRACP01161
Peptide Name D-Glu-Fniii14
Sequence TeATITGLEPGTEYTITVIAL
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| U-937 | Adult acute monocytic leukemi; Acute monoblastic/monocytic leukemia | Leukemia | As show in fig3 | WST-1 assay | 24 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification e=D-Glutamic acid
Chiral Mix
Physicochemical Information
Formula C93H152N20O31
Absent amino acids CDFHKMNQRSW
Common amino acids T
Mass 240327
Pl 3.61
Basic residues 0
Acidic residues 2
Hydrophobic residues 8
Net charge -2
Boman Index 496
Hydrophobicity 66.67
Aliphatic Index 116.19
Half Life
/
Extinction Coefficient cystines 1490
Absorbance 280nm 74.5
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP2716297B1
Patent Title D-Glu-Fniii14 Polypeptide for Use in Treating Cancer
Other Iinformation Granted Patent; Family: 8s / 8ex; Family Jurisdictions: JP, WO, US, EP; Legal Status: Active; Application No: 12758028; Filed: Mar 9, 2012; Published: Sep 27, 2017; Earliest Priority: Mar 11, 2011; Granted: Sep 27, 2017
Other Published ID EP2716297A4 EP2716297B1 JP5924593B2 JPWO2012124641A1 US2014005120A1 US9327013B2 WO2012124641A1
This work is licensed under a Creative Commons Attribution 4.0 International License.