This work is licensed under a Creative Commons Attribution 4.0 International License.
Not available
General Information
DRACP ID DRACP01162
Peptide Name Not available
Sequence TEATITGLEPGTEYTITVIAL
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| U-937 | Adult acute monocytic leukemi; Acute monoblastic/monocytic leukemia | Leukemia | As show in fig3 | WST-1 assay | 24 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C98H161N21O35
Absent amino acids CDFHKMNQRSW
Common amino acids T
Mass 255040
Pl 3.47
Basic residues 0
Acidic residues 3
Hydrophobic residues 8
Net charge -3
Boman Index -185
Hydrophobicity 50
Aliphatic Index 116.19
Half Life
Mammalian: 7.2 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 74.5
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP2716297B1
Patent Title D-Glu-Fniii14 Polypeptide for Use in Treating Cancer
Other Iinformation Granted Patent; Family: 8s / 8ex; Family Jurisdictions: JP, WO, US, EP; Legal Status: Active; Application No: 12758028; Filed: Mar 9, 2012; Published: Sep 27, 2017; Earliest Priority: Mar 11, 2011; Granted: Sep 27, 2017
Other Published ID EP2716297A4 EP2716297B1 JP5924593B2 JPWO2012124641A1 US2014005120A1 US9327013B2 WO2012124641A1
This work is licensed under a Creative Commons Attribution 4.0 International License.