This work is licensed under a Creative Commons Attribution 4.0 International License.
PBP-1
General Information
DRACP ID DRACP01166
Peptide Name PBP-1
Sequence CLQKTPKQC
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| CT26 | Mouse colon adenocarcinoma | Carcinoma | As show in fig4 | Mouse model anti-tumor assay | 24 days | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C43H77N13O13S2
Absent amino acids ADEFGHIMNRSVWY
Common amino acids CKQ
Mass 119117
Pl 8.82
Basic residues 2
Acidic residues 0
Hydrophobic residues 1
Net charge 2
Boman Index -1727
Hydrophobicity -92.22
Aliphatic Index 43.33
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 125
Absorbance 280nm 15.63
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID EP3725799A1
Patent Title Peptide Bound to Pl-L1 and Use Thereof
Other Iinformation Patent Application; Family: 5s / 6ex; Family Jurisdictions: EP, KR, US; Legal Status: Pending; Application No: 18888477; Filed: Dec 17, 2018; Published: Oct 21, 2020; Earliest Priority: Dec 15, 2017
Other Published ID EP3725799A4 KR102150419B1 KR20190072466A US2021163534A1
This work is licensed under a Creative Commons Attribution 4.0 International License.