This work is licensed under a Creative Commons Attribution 4.0 International License.
PvVespk
General Information
DRACP ID DRACP01173
Peptide Name PvVespk
Sequence GRPPGFSPFRSG
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| SK-OV-3 | Ovarian serous cystadenocarcinoma | Carcinoma | AS show in fig4,it could confirm effectively using as the therapeutic agent for the cancer treatment | MTT assay | 24h, 72h | Patent |
| OVCAR-3 | High grade ovarian serous adenocarcinoma | Carcinoma | AS show in fig4,it could confirm effectively using as the therapeutic agent for the cancer treatment | MTT assay | 24h, 72h | Patent |
Hemolytic Activity Human red blood cell: show very low hemolytic activity
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C57H84N18O15
Absent amino acids ACDEHIKLMNQTVWY
Common amino acids GP
Mass 145776
Pl 12.5
Basic residues 2
Acidic residues 0
Hydrophobic residues 2
Net charge 2
Boman Index -2786
Hydrophobicity -91.67
Aliphatic Index 0
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID KR101990437B1
Patent Title Peptide from Parapolybia varia having antitumor activity and uses thereof
Other Iinformation Granted Patent; Family: 2s / 2ex; Family Jurisdictions: KR; Legal Status: Active; Application No: 20170037330; Filed: Mar 24, 2017; Published: Jun 19, 2019; Earliest Priority: Mar 24, 2017; Granted: Jun 19, 2019
Other Published ID KR101990437B1
This work is licensed under a Creative Commons Attribution 4.0 International License.