This work is licensed under a Creative Commons Attribution 4.0 International License.
Not available
General Information
DRACP ID DRACP01177
Peptide Name Not available
Sequence IKWKAILDAVKKVL
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Not available
Type Synthetic peptide
Classification
Active ACP
Activity Information
| Cell Line | Disease | Cancer Classified | Activity | Assay | Testing Time | Literature |
|---|---|---|---|---|---|---|
| SK-OV-3 | Ovarian serous cystadenocarcinoma | Carcinoma | it could confirm that the proliferation of the ovarian cancer cell was statistically carefully reduced in the culture medium containing the peptide of the concentration more than 25mM cultivated for 2 | MTT assay | 24 h | Patent |
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antitumor; Antimicrobial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C79H137N19O17
Absent amino acids CEFGHMNPQRSTY
Common amino acids K
Mass 185716
Pl 10.8
Basic residues 4
Acidic residues 1
Hydrophobic residues 9
Net charge 3
Boman Index 279
Hydrophobicity 61.43
Aliphatic Index 167.14
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID KR20160119943A
Patent Title Peptide has antimicrobial antifungal and antitumor activity and uses thereof
Other Iinformation Patent Application; Family: 2s / 2ex; Family Jurisdictions: KR; Legal Status: Active; Application No: 20150048678; Filed: Apr 6, 2015; Published: Oct 17, 2016; Earliest Priority: Apr 6, 2015; Granted: Dec 26, 2017
Other Published ID KR101810630B1
This work is licensed under a Creative Commons Attribution 4.0 International License.