Sequence 9 from Patent US 20020137896
General Information
DRACP ID DRACP01215
Peptide Name Sequence 9 from Patent US 20020137896
Sequence ETLQQTLDASRGVTTLPLGVERRTDNPIYVTWTGADTVLGDVPKSPRFALVTETRVTK
Sequence Length 58
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C280H459N79O90
Absent amino acids CHM
Common amino acids T
Mass 738907
Pl 6.7
Basic residues 7
Acidic residues 7
Hydrophobic residues 19
Net charge 0
Boman Index -11672
Hydrophobicity -34.31
Aliphatic Index 87.24
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 6990
Absorbance 280nm 122.63
Polar residues 19
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2002/0137896 A1
Patent Title Antitumor protein and gene encoding same.
Other Iinformation Granted Patent Family: 3s / 5ex; Family Jurisdictions: US; Legal Status: Expired; Application No: 91196901; Filed:Jul 24, 2001; Published: Sep 26, 2002; Earliest Priority: Feb 13, 1997; Granted: Jul 13, 2004