Sequence 6 from Patent US 20020137896
General Information
DRACP ID DRACP01216
Peptide Name Sequence 6 from Patent US 20020137896
Sequence FVNIINGALQPISISPSDTYQPTLAVAAWAPPIDPAEGQLVIMGHNPNQEAGLNLPGSAVT
Sequence Length 61
UniProt ID Q8J2V8
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C282H441N73O87S
Absent amino acids CKR
Common amino acids AP
Mass 734853
Pl 3.74
Basic residues 1
Acidic residues 4
Hydrophobic residues 25
Net charge -3
Boman Index -1541
Hydrophobicity 17.87
Aliphatic Index 102.46
Half Life
Mammalian: 1 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 6990
Absorbance 280nm 116.5
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2002/0137896 A1
Patent Title Antitumor protein and gene encoding same.
Other Iinformation Granted Patent Family: 3s / 5ex; Family Jurisdictions: US; Legal Status: Expired; Application No: 91196901; Filed:Jul 24, 2001; Published: Sep 26, 2002; Earliest Priority: Feb 13, 1997; Granted: Jul 13, 2004