This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 14 from Patent US 20020137896
General Information
DRACP ID DRACP01220
Peptide Name Sequence 14 from Patent US 20020137896
Sequence LREWEAGVTDTYGMPQPTFHVKRTNADGDRDQRMMNDMTNVANMLGGYLP
Sequence Length 50
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C242H376N72O78S5
Absent amino acids CIS
Common amino acids DGMTNR
Mass 657658
Pl 4.77
Basic residues 6
Acidic residues 7
Hydrophobic residues 11
Net charge -1
Boman Index -12381
Hydrophobicity -85.4
Aliphatic Index 46.8
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 8480
Absorbance 280nm 173.06
Polar residues 16
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2002/0137896 A1
Patent Title Antitumor protein and gene encoding same.
Other Iinformation Granted Patent Family: 3s / 5ex; Family Jurisdictions: US; Legal Status: Expired; Application No: 91196901; Filed:Jul 24, 2001; Published: Sep 26, 2002; Earliest Priority: Feb 13, 1997; Granted: Jul 13, 2004
This work is licensed under a Creative Commons Attribution 4.0 International License.