This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 4 from Patent US 20020137896
General Information
DRACP ID DRACP01223
Peptide Name Sequence 4 from Patent US 20020137896
Sequence PIRLSKEKINDLLQRSQGDLTSSQHEIVHFTDVFIAGSGPISCTYARHIIDNTSTTK
Sequence Length 57
UniProt ID Not available
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C276H446N80O89S
Absent amino acids MW
Common amino acids IST
Mass 734017
Pl 7.62
Basic residues 9
Acidic residues 6
Hydrophobic residues 17
Net charge 3
Boman Index -11727
Hydrophobicity -38.6
Aliphatic Index 88.95
Half Life
Mammalian: >20 hour
Yeast: >20 hour
E.coli: ?
Extinction Coefficient cystines 1490
Absorbance 280nm 26.61
Polar residues 20
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2002/0137896 A1
Patent Title Antitumor protein and gene encoding same.
Other Iinformation Granted Patent Family: 3s / 5ex; Family Jurisdictions: US; Legal Status: Expired; Application No: 91196901; Filed:Jul 24, 2001; Published: Sep 26, 2002; Earliest Priority: Feb 13, 1997; Granted: Jul 13, 2004
This work is licensed under a Creative Commons Attribution 4.0 International License.