This work is licensed under a Creative Commons Attribution 4.0 International License.
Sequence 8 from Patent US 20020137896
General Information
DRACP ID DRACP01224
Peptide Name Sequence 8 from Patent US 20020137896
Sequence QEFDALLERAKTLLNVHSDQYDDSIRQIVVK
Sequence Length 31
UniProt ID Q8J2V8
PubChem CID Not available
Origin Synthetic construct
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Antitumor
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Not available
C-terminal Modification Not available
Other Modification None
Chiral L
Physicochemical Information
Formula C160H259N45O52
Absent amino acids CGMPW
Common amino acids DL
Mass 418040
Pl 4.7
Basic residues 5
Acidic residues 6
Hydrophobic residues 12
Net charge -1
Boman Index -7863
Hydrophobicity -49.68
Aliphatic Index 110
Half Life
Mammalian: >20 hour
Yeast: >20 hour
E.coli: ?
Extinction Coefficient cystines 1490
Absorbance 280nm 49.67
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US 2002/0137896 A1
Patent Title Antitumor protein and gene encoding same.
Other Iinformation Granted Patent Family: 3s / 5ex; Family Jurisdictions: US; Legal Status: Expired; Application No: 91196901; Filed:Jul 24, 2001; Published: Sep 26, 2002; Earliest Priority: Feb 13, 1997; Granted: Jul 13, 2004
This work is licensed under a Creative Commons Attribution 4.0 International License.