Sequence 8 from Patent US 20030077289

General Information


DRACP ID  DRACP01233

Peptide Name   Sequence 8 from Patent US 20030077289

Sequence  GALFLGWLGAAGSTMGAWSQPKKKRKV

Sequence Length  27

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic construct

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Antitumor



Structure Information


PDB ID  Not available

Predicted Structure  DRACP01233

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Not available

C-terminal Modification  Not available

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C131H209N37O32S

Absent amino acids  CDEHINY

Common amino acids  G

Mass  331034

Pl  12

Basic residues  5

Acidic residues  0

Hydrophobic residues  11

Net charge  5

Boman Index  -1130

Hydrophobicity  -14.07

Aliphatic Index  68.89

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: >10 hour

Extinction Coefficient cystines  11000

Absorbance 280nm  423.08

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US 2003/0077289 A1

Patent Title  Use of cell-penetrating peptides to generate antitumor immunity.

Other Iinformation  Granted Patent Family: 6s / 6ex; Family Jurisdictions: CN, WO, AU, US; Legal Status: Discontinued; Application No: 7755502; Filed:Feb 15, 2002; Published: Apr 24, 2003; Earliest Priority: Feb 15, 2001

Other Published ID  CN1309417C  CN1503628A  WO2002064057A2  WO2002064057A3 




DRACP is developed by Dr.Zheng's team.